The Journal of Scleroderma and Related Disorders, the official independent journal of the World Scleroderma Foundation and EUSTAR, is an international, multi-disciplinary, peer-reviewed publication targeted to scientists and clinicians interested in systemic sclerosis, scleroderma, and other related autoimmune and fibrotic diseases.The journal publishes high quality, original research articles on the epidemiology, natural history, pathophysiology, diagnosis, treatment and outcome of these diseases as well as reviews and thought-provoking editorials and commentaries, with the aim of becoming the leading worldwide reference journal in the field of scleroderma and related diseases.
Recent JSRD publications
Highlights from Congresses
We are delighted to present to you the highlights from the most updated research results in the scleroderma field presented at international congresses: a selection from oral and poster presentation sessions. [...]
Selexipag treatment in patients with systemic sclerosis–associated pulmonary arterial hypertension in clinical practice, a case series
Abstract Objective: To describe the efficacy and safety in all patients with systemic sclerosis–associated pulmonary arterial hypertension who started selexipag between 09-2016 and 06-2018 in two pulmonary arterial hypertension expert centers. Methods: All patients with [...]
Characteristics of patients with systemic sclerosis suffering from a lower limb amputation: Results of a French collaborative study
Abstract Objective: Systemic sclerosis mainly affects the microvascular network. However, macrovascular manifestations have been reported. We aimed to investigate the characteristics of systemic sclerosis patients with an amputation of a lower limb segment. Methods: We [...]
Improving adherence to pulmonary hypertension screening in patients with systemic sclerosis: Overcoming the provider-level barriers
Abstract Objective: Pulmonary arterial hypertension is a life-limiting complication in patients with systemic sclerosis. Current recommendations suggest a minimum screening of an annual transthoracic echocardiogram and pulmonary function test. We hypothesize that modifiable provider-level hurdles [...]
Ulnar artery vasculopathy: a common but nonspecific feature of systemic sclerosis
Abstract IntroductionSystemic sclerosis (SSc) is characterized by microvascular abnormalities and fibrosis. Several studies have reported that large vessel disease is also common in SSc. The aim of this case series was to investigate whether ulnar [...]
Use of intravenous epoprostenol as a treatment for the digital vasculopathy associated with the scleroderma spectrum of diseases
Abstract IntroductionIntravenous prostanoid therapy is recommended for severe systemic sclerosis-related digital vasculopathy. The evidence supporting this recommendation is limited. The aim of this study was to evaluate the safety and efficacy of treating scleroderma spectrum [...]
A randomized, single-blinded cross-over trial of ischemic preconditioning in Raynaud’s phenomenon
A randomized, single-blinded cross-over trial of ischemic preconditioning in Raynaud’s phenomenon Abstract IntroductionIschemic preconditioning (IPC) is protective against future ischemia, with brief cycles of ischemia and reperfusion leading to the release of circulating endogenous compounds [...]
Certainties and uncertainties concerning the contribution of pericytes to the pathogenesis of systemic sclerosis
Certainties and uncertainties concerning the contribution of pericytes to the pathogenesis of systemic sclerosis Abstract The role of pericytes in systemic sclerosis (SSc) is unclear because of the difficulty in phenotyping them. They are mainly [...]
Paul Klee’s illness – a series of historical and clinical vignettes
Paul Klee’s illness – a series of historical and clinical vignettes Post author correction Article Type: BRIEF REPORT Article Subject: Psychology and Social Phenomena DOI:10.5301/jsrd.5000248 Authors Richard M. Silver Abstract Paul Klee (1879-1940) is undoubtedly [...]
Differential expression of hepatocyte growth factor in patients with systemic sclerosis-associated pulmonary arterial hypertension
Differential expression of hepatocyte growth factor in patients with systemic sclerosis-associated pulmonary arterial hypertension Post author correction Article Type: BRIEF REPORT Article Subject: Epidemiology and Diagnostic Methods DOI:10.5301/jsrd.5000245 Authors Yon K. Sung, Roham T. Zamanian, [...]
Prevalence and incidence of pulmonary arterial hypertension: 10-year follow-up of an unselected systemic sclerosis cohort
Prevalence and incidence of pulmonary arterial hypertension: 10-year follow-up of an unselected systemic sclerosis cohort Post author correction Article Type: ORIGINAL RESEARCH ARTICLE Article Subject: Epidemiology and Diagnostic Methods DOI:10.5301/jsrd.5000246 Authors Els Vandecasteele, Karin Melsens, [...]
Validity of the PROMIS-29 in a large Australian cohort of patients with systemic sclerosis
Validity of the PROMIS-29 in a large Australian cohort of patients with systemic sclerosis Post author correction Article Type: ORIGINAL RESEARCH ARTICLE Article Subject: Epidemiology and Diagnostic Methods DOI:10.5301/jsrd.5000243 Link Validity of the PROMIS-29 in [...]
Functional autoantibodies directed against cell surface receptors in systemic sclerosis
Functional autoantibodies directed against cell surface receptors in systemic sclerosis Post author correction Article Type: REVIEW Article Subject: Clinical Conditions and Organ Involvement DOI:10.5301/jsrd.5000241 Link: Functional autoantibodies directed against cell surface receptors in systemic sclerosis [...]
Volume 2 Issue 1 of the Journal of Scleroderma and Related Disorders
The Journal of Scleroderma and Related Disorders (JSRD), the official journal of the World Scleroderma Foundation and EUSTAR, is an international, multi-disciplinary, peer-reviewed publication targeted to scientists and clinicians interested in systemic sclerosis, scleroderma, and [...]
The critical need for accurately defining digital ulcers in scleroderma
The critical need for accurately defining digital ulcers in scleroderma J scleroderma relat disord 2017; 2(2): 69 - 71 Article Type: EDITORIAL DOI:10.5301/jsrd.5000238 Authors Wendy Li, Tracy M. Frech Abstract Digital ulcers are one of [...]
