e-Masterclass on ILD in SSc, China, December 10th-17th, 2021

2021-12-03T14:13:18+01:00

e-Masterclass on ILD in SSc China, December 17th, 2021 Kindly note that the time zone is Beijing time DOWNLOAD THE PROGRAM On-demand pre-recorded lectures available from December 10th, 2021.  REGISTRATION TO THE MASTERCLASS PLATFORM Steering committee: WSF and Chinese Officers Pre-recorded lectures available from [...]

e-Masterclass on ILD in SSc, Germany, December 18th, 2020

2020-11-25T09:42:32+01:00

e-Masterclass on ILD in SSc Germany, December 18th, 2020 Kindly note that the time is in MEZ (UTC+01:00) DOWNLOAD THE PROGRAM On demand pre-recorded lectures available from December 4th to December 18th LIVE SESSION on December 18th, 2020 REGISTRATION TO THE MASTERCLASS PLATFORM [...]

e-Masterclass on ILD in SSc, Japan, November 13th, 2020

2020-11-06T09:18:59+01:00

e-Masterclass on ILD in SSc Japan, November 13th, 2020 Kindly note that the time is in JST (UTC +9) DOWNLOAD THE PROGRAM On demand pre-recorded lectures available from October 30th, 2020 to November 13th, 2020 REGISTRATION TO THE MASTERCLASS PLATFORM ORGANIZER: PROF. MASATAKA [...]

BASIC SCIENCE JOURNAL CLUB OF EUSTAR YIG May-August 2019

2019-10-22T10:06:21+02:00

May CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis. June Blockade of the CX3CL1-CX3CR1 Pathway Inhibits the Progress of Skin Inflammation, Fibrosis, and Vascular Injury in an Experimental Mouse Model of Systemic Sclerosis July Microparticles in systemic sclerosis: Potential pro-inflammatory mediators and pulmonary hypertension biomarkers. August Activation of [...]

BASIC SCIENCE JOURNAL CLUB OF EUSTAR YIG SEP DEC 2018

2019-10-22T09:47:52+02:00

READ MORE The Nrf2-Antioxidant Response Element SignallingPathway Controls Fibrosis and Autoimmunity in Scleroderma. Dysregulationsintheoxidant/antioxidantbalanceareknowntobemajorfactorsinthepathogenesisofsystemicsclerosis(SSc).NRF2actsasakeyplayerintheantioxidantdefensebycontrollingthetranscriptionofantioxidantandcytoprotectivegenes.Inthisarticle,theauthorsexploredtheinvolvementofadown-expressionofNRF2inthepathogenesisofSScandtherelevanceofaNRF2agonist,asapotenttherapeuticoptioninSSc.

BASIC SCIENCE JOURNAL CLUB OF EUSTAR YIG May–Aug 2018

2019-10-21T22:46:14+02:00

READ MORE May 2018 Poly(ADP-ribose) polymerase-1 (PARP-1) regulates fibroblast activation in systemic sclerosis. The enzyme poly(ADP-ribose) polymerase-1 also called PARP-1, is a member of the PARP family, a group of 18 enzymes that transfer ADP-ribose groups onto various substrate proteins. This mechanism called PARylation, exerts profound regulatory effects on many physiological and pathological processes. Among [...]

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